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ABOUT THE SUSTAINABLE HIV PREVENTION INITIATIVE

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The Sustainable HIV Prevention Initiative emerged from multi-country discussions at the 22nd International Conference on AIDS and STIs in Africa (ICASA), held in December 2023 in Harare, Zimbabwe. The Initiative aims to share and advance country-led sustainable HIV prevention responses, such as Malawi’s Blantyre Prevention Strategy, and to examine and deepen the understanding of core capabilities and health system functions that define the “how” of sustainable HIV prevention programming in sub-Saharan Africa.

 

It is funded by a grant from the Gates Foundation and co-chaired by leaders from Malawi’s National AIDS Commission, Ministry of Health, and Georgetown University’s Center for Innovation in Global Health. It is also supervised by a Steering Committee consisting of individuals with prevention expertise and extensive experience overseeing and coordinating HIV prevention efforts. The initiative has two major deliverables:

 

  • A convening of government and technical experts and;

  • A series of papers to be published in the Lancet HIV and Lancet Global Health.

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LAUNCH OF THE LANCET HIV & THE LANCET GLOBAL HEALTH JOINT SERIES ON SUSTAINABLE HIV PREVENTION IN AFRICA

On December 4, 2025, at the International Conference on AIDS and STIs In Africa (ICASA), The Lancet HIV (TLHIV) & The Lancet Global Health (TLGH) Joint Series on Sustainable HIV Prevention in Africa was launched. This six-paper series, jointly published in The Lancet HIV & The Lancet Global Health, focused on strengthening health systems’ capacity for sustainable HIV prevention while advancing broader health system goals. The series explores themes such as systemic integration of HIV prevention into public health systems; systematic community engagement; nationally led new product introduction; and leveraging digital health and artificial intelligence to expand reach and improve program efficiency. The paper titles are as follows:

 

FEBRUARY 2025 SUSTAINABLE HIV PREVENTION CONVENING

The Sustainable HIV Prevention Initiative convened leaders from the National AIDS Coordinating Authorities and HIV directorates of 11 African countries, along with local and global technical and civil society experts in Lilongwe, Malawi, in February 2025.

 

The countries represented were:

 

  • Eswatini

  • Ghana

  • Kenya​

  • Malawi

  • ​Nigeria

  • Rwanda

  • South Africa

  • Tanzania

  • ​​Uganda

  • Zambia

  • Zimbabwe​​​

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The meeting aimed to:

 

  • Deepen the dialogue by moving beyond the WHAT to the HOW of sustainable HIV response, ensuring efforts are embedded within strong, resilient health systems.

  • Highlight critical health systems innovations from countries in the region that demonstrate practical, scalable solutions.

  • Discuss actions being taken by governments, civil society, and other stakeholders in response to disruptions in U.S. foreign assistance.

  • Ensure these insights inform national and donor-promoted sustainability dialogues, including through the forthcoming Lancet HIV and Lancet Global Health paper series.

 

The discussions deepened the group’s collective understanding of the seismic shifts in the external funding environment for HIV programs and accelerated conversations on the core health system functions and capabilities essential to sustaining and strengthening HIV programming. Participants highlighted emerging examples of nationally led policies and programs, with a focus on integrated HIV prevention approaches, the critical importance of long-acting HIV prevention technologies, and alignment with the needs of communities and affected populations. A report summarizing the convening is available here.

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Viewpoint: Following the convening, the Sustainable Prevention Initiative leaders authored a Viewpoint article titled “The Global HIV Response at a Crossroads: Protecting Gains and Advancing Sustainability Amid Funding Disruptions,” published in the Lancet HIV. The Viewpoint provides specific country-level insights into how funding disruptions threaten to reverse gains in the HIV response. It includes a series of recommendations for national leaders and calls on funders to support service delivery integration, fund high-priority underfunded areas, invest in health system resilience, and ensure access to long-acting pre-exposure prophylaxis (PrEP). The link to access the Viewpoint is available here.

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Policy Brief: 60 participants at the convening also endorsed a policy brief titled “Strengthening National Leadership for Sustainable HIV Programs: A Policy Brief for Government Leaders” The policy brief, developed for national political leaders, outlines key strategic priorities for governments to sustain their HIV response: increasing domestic financing, integrating HIV prevention and treatment within primary healthcare services, prioritizing prevention—including highly effective long-acting formulations—within national HIV agendas, and ensuring inclusive access to HIV services for vulnerable populations. The link to access the Policy Brief is available here.

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Press Release: A press release titled “Leaders from 11 African Countries Develop Policy Recommendations to Sustain and Strengthen Global HIV Response” was jointly issued by the Malawi National AIDS Commission, Ministry of Health, and Georgetown University Center for Innovation in Global Health on May 9, 2025, detailing these developments. The link to access the Press Release is available here.

Participants at the February 2025 Sustainable HIV Prevention Initiative convening.

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Ima John-Dada (Head of HIV Prevention, Federal Ministry of Health, Nigeria); Getrude Mbhalati (HIV Youth Manager, National Department of Health, South Africa); Dr. Gift Kawalazira (Director of Health and Social Services, Blantyre District Council, Malawi); Dr. Peter Mudiope (HIV Prevention Coordinator, Uganda AIDS Commission); Yohane Kamgwira (BPS Prevention Coordinator, National AIDS Commission, Malawi; Prof. Alister Munthali, Director of Programmes, PALM Consulting Limited

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Dr. Martias Joshua, Chief of Health Services - Reforms, Ministry of Health, Malawi, gives the keynote address

Representatives of the National AIDS Coordinating Authorities present at the February convening.

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